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Criteria for an Increased Specificity of MRI Interpretation in Elderly with Suspected Multiple Sclerosis Neurol 38:1822-1825, Fazekas,F.,et al, 1988 See this aricle in Pubmed Article Abstract We reviewed the MRIs of 49 asymptomatic volunteers(age range,31 to 77 years)and of 50 MS patients(age range,14 to 63)for areas of increased signal(AIS)and features discriminating MS lesions from lesions seen with normal aging.We obtained optimal specificity of MRI interpretation(100%)if we required at least two of the following three AIS features-size greater than or equal to 6 mm,abutting ventricular bodies,infratentorial location- for a positive MRI diagnosis of MS.Applying these criteria to the MRIs of elderly patients with suspected MS should significantly improve specificity(p<0.001)over current quantitative criteria(at least three AIS greater than or equal to 3 mm)without significantly decreasing sensitivity.

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(click to filter results - removes previous filter) MRI MRI,abnormal multiple sclerosis multiple sclerosis,diagnosis of multiple sclerosis,late-onset old age,neurology of

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